In Section 6, EPA has characterized its overall confidence in the quantitative and qualitative aspects of hazard and dose response. These documents provide information on the health effects of exposure, the chemical’s toxicity and material for responding to a chemical incident. (1) The odor threshold for vinyl chloride is 3,000 ppm. It can be formed when other substances such as trichloroethane, trichloroethylene, and tetrachloroethylene are broken down. Email: Contact CDC-INFO. The symptoms of vinyl chloride exposure are classified by ppm levels in ambient air with 4,000 ppmhaving a threshold effect. Vinyl chloride is a colorless gas with a mild, sweet odor. Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. Studies of workers in polyvinyl chloride polymerization of certain plastic and rubber factories revealed that numerous workers had been diagnosed with liver angiosarcoma. Vinyl chloride, a colourless, flammable, toxic gas belonging to the family of organohalogen compounds and used principally in making polyvinyl chloride, or PVC, a widely used plastic with numerous applications. The target organs for VC now clearly in … The major industrial preparation of vinyl chloride begins with ethylene and has two Case Studies in Environmental Medicine. These clinics specialize in Prioritization of substances based on a combination of their frequency, toxicity, and potential for human exposure at National Priorities List (NPL) sites. Vinyl chloride monomer (VCM) is a colorless, gaseous, sweet-smelling organochloride primarily used in the production of polyvinyl chloride (PVC) with additional historical usage before the 1970s as an aerosol propellant and refrigerant. It is a manufactured substance that does not occur naturally. Small quantities of vinyl chloride can be released to food since it is used to make many food wrappings and containers. Addendum to the Toxicological Profile for Vinyl Chloride (February 2016). • Vinyl chloride is a colorless, flammable gas with a mild, sweet odor. Plasticized or Flexible PVC (Density: 1.1-1.35 g/cm3): Flexible PVC is formed by the addition of compatible plasticizers to PVC which lower the crystallinity. One reason why PVC is so toxic is that it is often mixed with softening chemicals called plasticizers, the most well known variety being phalates. ATSDR can also tell you the location of occupational and environmental health clinics. Prior to 1974, workers were commonly exposed to 1,000 ppm vinyl chloride, causing "vinyl chloride illness" such as acroosteolysis and Raynaud's Phenomenon. Vinyl chloride is a colorless gas. Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1990. PVC is used to make a variety of plastic products, including pipes, wire and cable coatings, and packaging materials. For more than 30 years, leading health, environmental justice, and health-impacted organizations across the country and world have been campaigning to phase out this poison plastic. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, Medical Management Guidelines (MMG) for Acute Chemical Exposure, Agency for Toxic Substances and Disease Registry, Quick Reference for Health Care Providers. These releases … (4) • The odor threshold for vinyl chloride ranges from 260 ppm to 4,000 ppm. It is a manufactured substance that does not occur naturally. Vinyl chloride is used to make polyvinyl chloride (PVC). Dubbed the most toxic plastic, vinyl – or polyvinyl chloride – is used today in a superfluity of items surrounding us. Vinyl chloride is a deadly toxic chemical, despite industry’s repeated attempts to hide the threats. Healthy Child Healthy World describes PVC as the most toxic plastic, and vinyl chloride, the chemical used to make PVC, has been described as a known carcinogen by the World Health Organization's International Agency for Research on Cancer. Water from the Tarawa Terrace Treatment Plant was contaminated by PCE (perchloroethylene or tetrachloroethylene). No other plastic contains or releases as many dangerous chemicals. Workers at facilities where vinyl chloride is produced or used may be exposed primarily through inhalation. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1997. It has a mild, sweet odor. Vinyl chloride is used to make polyvinyl chloride (PVC). Vinyl Chloride Toxicity. Toxic substances list: vinyl chloride Vinyl chloride (VC) is a flammable and explosive colourless gas with a sweet odour. ATSDR and Texas Department of State Health Services (DSHS) are conducting an extensive review of environmental health concerns raised by the community members in Midlothian, Texas to determine if chemical releases from local industries could or have affected the health of persons and animals in the area. Quick reference guide providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects for a substance. It burns easily and it is not stable at high temperatures. Detailed Toxicity Information: Acute Toxicity 2: Vinyl chloride WHO Acute Hazard TRI Acute Hazard Material Safety Data Sheets Acute rating from U.S. EPA product label U.S. NTP Acute Toxicity Studies View Studies Cholinesterase Inhibitor: Not Listed Not Listed Not … Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. What is disturbing is the fact that PVC uses chemicals that are quite dangerous to both our health and the environment; yet many of these chemicals are present in our own homes, workplaces and schools where children are exposed to them on a daily basis. It is used in the plastics industry, often to produce PVC (polyvinyl chloride) and does not occur naturally in the environment. Vinyl chloride causes angiosarcoma, brain and lung cancers, lymphoma, and leukemia. [1] [2][3] VCM is now classified as an International Agency for Research on Cancer (IARC) Group 1 carcinogen. The general population may be exposed by inhaling contaminated air or tobacco smoke. A recent study that was conducted found that vinyl flooring contains toxic chemicals that include phthalates, lead, flame retardants, and VOCs like formaldehyde that will off gas into the air after the installation process in a home and taint the indoor air quality to hazardous levels. Doctors pinpointed the carcinogenicity of vinyl chloride in the late 1960s. 888-232-6348 (TTY) From 1987 to 1993, according to EPA's Toxic Release Inventory, vinyl chloride releases to water and land totalled over 38,000 lbs. Vinyl chloride toxicity occurs mainly through occupational exposure during the polymerization of VCM into PVC; however, community exposures secondary to industrial spills have occurred. for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to vinyl chloride. Additionally, there are reports of cases of significant chronic exposure related to aerosol propellant usage in the 1960s and early 1970s, although VCM is no longer utilized in this manner. In 1982, the Marine Corps discovered specific volatile organic compounds (VOCs) in the drinking water provided by two of the eight water treatment plants on base. U.S. Marine Corps Base Camp Lejeune, North Carolina was established in 1942. These chemicals include dioxins that are among the most toxic chemicals known to science. Other pertinent literature is also presented, but is described in less detail than the key studies. [3] recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Summary: Vinyl chloride is a colorless gas. It has a mild, sweet odor. Vinyl Chloride is a cancer-causing chemical that is highly-toxic, flammable, colorless, and sweet-smelling. Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification. Vinyl chloride, a chemical known to cause cancer, poisons the air breathed by workers and people living in contaminated communities. Polyvinyl chloride is more often referred to by its less-technical names, PVC and vinyl. It is primarily used to make Polyvinyl Chloride (PVC), the 3rd most-popular plastic material in the world. For this reason, some items on this page will be unavailable. Note: Javascript is disabled or is not supported by your browser. The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. VC is the most toxic plastic for our health and environment. Vinyl chloride | H2C=CHCl or (C2H3Cl)n or C2H3Cl | CID 6338 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. Vinyl chloride has little acute toxicity, and air levels over 8000 ppm may be tolerated for 5 minutes without the development of symptoms. [Note: Shipped as a liquefied compressed gas.] [ifediba.com] The gas can cause dizziness, drowsiness, and headache when inhaled. In the environment, the highest levels of vinyl chloride are found in … Most of it is made in the United States. Vinyl chloride is also known as chloroethene, chloroethylene, and ethylene monochloride. Publication intended to aid emergency department physicians and other emergency healthcare professionals who manage acute exposures resulting from chemical incidents. Vinyl chloride is a colorless gas with a mildly sweet smell that is flammable. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Additional research has now demonstrated the carcinogenicity of VC to other organs and at lower concentrations. Toxic Exposure Injury Attorneys - Serving Clients Nationwide. Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. Vinyl chloride is a known animal and human carcinogen that induces angiosarcoma of the liver as well as tumors of the lung and hematolymphopoietic system in humans (Doll 1988; IARC 1987). Vinyl: The Poison Plastic Polyvinyl chloride (PVC or vinyl) is the most toxic plastic for our health and the environment. The intensity of symptoms varies fro… It can be formed when other substances such as trichloroethane, trichloroethylene, and tetrachloroethylene are broken down. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. Chloroethene, Chloroethylene, Ethylene monochloride, Monochloroethene, Monochloroethylene, VC, VCM, Vinyl chloride monomer (VCM) Colorless gas or liquid (below 7°F) with a pleasant odor at high concentrations. Longer exposures have been associated with headache, dizziness, euphoria, ataxia, and narcosis. Short-term exposure to moderate levels of vinyl chloride in the air can result in a headache, vertigo, loss of consciousness, and fatigue.Nervous system damage is also possible. Vinyl chloride is used to make polyvinyl chloride (PVC). vinyl chloride 100 75-01-4 Ingredient name % CAS number There are no additional ingredients present which, within the current knowledge of the supplier and in the (1) The chemical formula for vinyl chloride is C Exposure has also been associated with brain tumors. (4) • The chemical formula for vinyl chloride is C 2 H 3 Cl and the molecular weight is 62.5 g/mol. For this reason, some items on this page will be unavailable. [4] Vinyl chloride finds its major application in the production of PVC. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of vinyl chloride. An emerging toxic plastic of concern, polyvinyl chloride (PVC or vinyl), is used widespread in schools across the nation. It is volatile, so the primary exposure is via inhalation as against food or water with occupational hazards being highest. Toxicological Profile for Vinyl Chloride (Update). (4) Vinyl chloride is slightly soluble in water and is quite flammable. To sum up: During its lifecycle PVC plastic releases toxic, chlorine-based chemicals that build up in the world’s ecosystems and end up in the food chain and eventually in humans and animals. Agency for Toxic Substances and Disease Registry (ATSDR). According to the Agency for Toxic Substances & Disease Registry, an organization under the Centers for Disease Control and Prevention, vinyl chloride is extremely toxic if inhaled, and it can cause major injuries if exposed to the skin directly. Note: Javascript is disabled or is not supported by your browser. Most often used in construction, PVC is a plastic composed of three elements: carbon, hydrogen and chlorine. It is used to make PVC, which is an ingredient in making plastic products, such as pipes, wire and cable coatings, and packaging materials. 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